DESAFIOS NO DIAGNÓSTICO DE INFECÇÕES ASSINTOMÁTICAS POR PLASMODIUM: EXPLORANDO O PAPEL DOS PORTADORES ASSINTOMÁTICOS COMO RESERVATÓRIO NA MANUTENÇÃO DO CICLO DA DOENÇA
Palavras-chave:
Malária, Infecções Assintomáticas, Diagnóstico, Imunologia, PlasmodiumResumo
A malária assintomática (infecção silenciosa por Plasmodium) ainda apresenta muitos desafios diagnósticos. Diante desse problema, este artigo de revisão possui os objetivos de explicar como portadores assintomáticos da infecção servem como reservatório da doença colaborando para a manutenção de seu ciclo, a atuação do sistema imunológico e os testes diagnósticos existentes, bem como suas limitações. Foi realizada uma análise de informações obtidas nos últimos 20 anos, tendo como ferramentas de busca: Biblioteca Virtual em Saúde, U.S. National Library of Medicine, PubMed Central (PMC) e Scientific Electronic Library Online. Após essa análise foi possível compreender como a malária assintomática ocorre e contribui para a persistência do Plasmodium em áreas endêmicas, um dos maiores desafios na erradicação da doença no Brasil e nos demais países com casos autóctones, além de identificar as limitações existentes em todos os métodos atualmente utilizados para o diagnóstico e controle de infectados.
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